All Years
============
2020
============
63
Asymmetric clustering of centrosomes defines the early evolution of tetraploid
cells.
Baudoin N.C., Nicholson J.M., Soto K., Martin O., Chen J.,
Cimini D.
(2020).
eLife 9, e54565
============
2019
============
62
Aneuploidy and gene expression: is there dosage compensation?
Kojima S. and
Cimini D. (2019).
Epigenomics, 11: 1827-1837.
61
Chromosomes missegregated into micronuclei contribute to chromosomal instability
by missegregating
at the next division.
He B., Gnawali N., Hinman A.W., Mattingly A.J., Osimani A.,
Cimini D.
(2019).
Oncotarget, 10: 2660-2674.
60
Exogenous glucocorticoids amplify the costs of infection by reducing resistance
and tolerance,
but effects are mitigated by co-infection.
Schoenle L.A., Moore I.T., Dudek A.M., Garcia E.B., Mays M., Haussmann M.F.,
Cimini
D., Bonier F.
(2019).
Proceedings of the Royal Society B: Biological Sciences, 286: 20182913.
59
Single-cell analysis reveals that chronic silver nanoparticle exposure induces
cell division defects
in human epithelial cells.
Garcia E.B., Alms C., Hinman A.W., Kelly C., Smith A., Vance M., Loncarek J., Marr L.C.,
Cimini D.
(2019).
International Journal of Environmental Research and Public Health, 16: 2061.
58
Environmental stresses induce karyotypic instability in colorectal cancer cells.
Tan Z., Chan Y.J.A., Chua Y.J.K., Rutledge S.D., Pavelka N.,
Cimini D.,
Rancati G. (2019).
Molecular Biology of the Cell, 30: 42-55.
============
2018
============
57
Chromosome segregation: the bigger they come, the harder they fall.
Baudoin N.C. and
Cimini D. (2018).
Current Biology, 28: R665–R667.
56
A guide to classifying
mitotic stages and mitotic
defects in fixed cells.
Baudoin N.C. and
Cimini D. (2018).
Chromosoma, 127: 215-227.
55
Fluid shear stress impacts
ovarian cancer cell viability, subcellular organization, and promotes
genomic instability.
Hyler A.R., Baudoin N.C., Brown M.S., Stremler M.A.,
Cimini D., Davalos
R.V., Schmelz E.M. (2018).
PLoS ONE, 13: e0194170.
54
Near-tetraploid cancer cells
show chromosome instability triggered by replication stress and exhibit
enhanced invasiveness.
Wangsa D., Quintanilla I., Torabi K., Vila-Casadesús M., Ercilla A., Klus G., Yuce Z.,
Galofré C.,
Cuatrecasas M., Lozano J.J., Agell N.,
Cimini
D., Castells A., Ried T., and Camps J. (2018).
FASEB Journal, 32: 3502-3517.
============
2017
============
53
Transient ALT activation
protects human primary cells from chromosome instability induced by
low chronic oxidative stress.
Coluzzi E., Buonsante R., Leone S., Asmar A.J., Miller K.L.,
Cimini D., and
Sgura A. (2017).
Scientific Reports, 7: 43309.
============
2016
============
52
Laser microsurgery reveals
conserved viscoelastic behavior of the kinetochore.
Cojoc G., Roscioli E., Zhang L., García-Ulloa A., Shah J.V., Berns M.W., Pavin N.,
Cimini D., Tolić I.M.,
and Gregan J. (2016).
The Journal of Cell Biology , 212: 767-776.
[Highlighted in commentary by Cabello, Gachet, and
Tournier published in the same issue]
51
Selective advantage of
trisomic human cells cultured in non-standard conditions.
Rutledge S.D., Douglas T.A., Nicholson J.M., Vila-Casadesús M., Kantzler C.L., Wangsa D.,
Barroso-Vilares M.,
Kale S.D., Logarinho E., and
Cimini D.
(2016)
Sci. Rep., 6: 22828.
50
Consequences of aneuploidy in
sickness and in health.
Rutledge S.D. and
Cimini D. (2016)
Curr. Opin. Cell Biol., 40: 41-46.
49
Using photoactivatable GFP to
study microtubule dynamics and chromosome segregation.
He B. and
Cimini D. (2016)
Methods Mol. Biol., 1413: 15-31.
48
Chromosome
bridges maintain kinetochore-microtubule attachments throughout mitosis
and rarely break during anaphase.
Pampalona J., Roscioli E., Silkworth W.T., Bowden B., Genescà A., Tusell L., and
Cimini D. (2016)
PLoS ONE, 11:e0147420.
47
Overlap microtubules link
sister k-fibres and balance the forces on bi-oriented kinetochores.
Kajtez J., Solomatina A., Novak M., Polak B., Vukušić K., Rüdiger J., Cojoc G., Milas A.,
Šumanovac Šestak I.,
Risteski P., Tavano F., Klemm A.H., Roscioli E.,
Welburn J.,
Cimini D., Glunčić M., Pavin N., and Tolić I.M. (2016)
Nat. Commun., 7:10298.
46
The centrosome: a multifaceted
cellular weapon against chromosome instability.
Guarguaglini G. and
Cimini D. (2016)
Chromosome Res., 24: 1-4.
============
2015
============
45
Aurora A kinase contributes to
a pole-based error correction pathway.
Ye A.A., Deretic J., Hoel C.M., Hinman A.W.,
Cimini D., WelburnJ.P., and
MarescaT.J. (2015)
Curr. Biol., 25: 1842-1851.
44
Characterization of
conventional one-step sodium thiosulfate facilitated gold nanoparticle
synthesis.
Saverot S.E., Reese L.M.,
Cimini D., Vikesland P.J, and Bickford L.R.
(2015)
Nanoscale Res. Lett., 10: 940.
43
Chromosome mis-segregation and
cytokinesis failure in trisomic human cells.
Nicholson J.M., Macedo J.C., Mattingly A.J., Wangsa D., Camps J., Lima V., Gomes A.M., Dória
S., Ried T.,
Logarinho E., and
Cimini D. (2015)
eLife, 4: e05068.
42
Genomic instability: crossing
pathways at the origin of structural and numerical chromosome changes.
Russo A., Pacchierotti F.,
Cimini D., Ganem N.J., Genescà A., Natarajan
A.T., Pavanello S.,
Valle G., and Degrassi F. (2015)
Environ. Mol. Mutagenesis, 56: 563-580.
41
Link between aneuploidy and
chromosome instability.
Nicholson J.M. and
Cimini D. (2015)
Internat. Rev. Cell Mol. Biol., 315: 299-317.
============
2014
============
40
Modeling chromosome dynamics
in mitosis: a historical perspective on models of metaphase
and anaphase in eukaryotic cells.
Civelekoglu-Scholey G. and
Cimini D. (2014)
Interface Focus, 4: 20130073.
39
The mitotic origin of
chromosomal instability.
Bakhoum S.F., Silkworth W.T., Nardi I.K., Nicholson J.M., Compton D.A., and
Cimini
D. (2014)
Curr. Biol., 24: R148-149.
============
2013
============
38
Cancer karyotypes: survival of
the fittest.
Nicholson J.M. and
Cimini D. (2013)
Front. Oncol., 3: 148.
37
Cyclophilin 20-3 Relays a
12-Oxo-Phytodienoic Acid Signal During Stress Responsive Regulation
of Cellular Redox Homeostasis.
Park S.W., Li W., Viehhauser A., He B., Kim S., Nilsson A.K., Andersson M.X., Kittle J.D.,
Ambavaram M.M.R.,
Luan S., Esker A.R., Tholl D.,
Cimini D., Ellerstrom M., Coaker G., Mitchell T.K., Pereira A., Dietz K.J.,
and Lawrence C.B. (2013)
Proc. Natl. Acad. Sci. U.S.A., 110: 9559-9564.
36
MISP: the missing link between
extracellular matrix and astral microtubules.
Nain A. and
Cimini D. (2013)
Cell Cycle, 12:1821-1822.
35
Dynamic bonds and polar
ejection force distribution explain kinetochore oscillations in PtK1
cells.
Civelekoglu-Scholey G., He B., Shen M., Wan X., Roscioli E., Bowden B., and
Cimini
D. (2013)
J. Cell Biol., 201: 577-593.
============
2012
============
34
Transient defects of mitotic
spindle geometry and chromosome segregation errors.
Silkworth W.T. and
Cimini D. (2012)
Cell Div., 7: 19.
33
Doubling the deck: tetraploidy
induces chromosome shuffling and cancer.
Nicholson J.M. and
Cimini D. (2012)
Cell Cycle, 18: 3355.
32
The coupling between sister
kinetochore directional instability and oscillations in centromere stretch
in metaphase PtK1 cells.
Wan X.,
Cimini D., Cameron L.A., and Salmon E.D. (2012)
Mol. Biol. Cell, 23: 1035-1046.
31
Timing of centrosome
separation is important for accurate chromosome segregation.
Silkworth W.T., Nardi I.K., Paul R., Mogilner A., and
Cimini D. (2012)
Mol. Biol. Cell, 23: 401-411.
============
2011
============
30
How mitotic
errors contribute to karyotypic diversity in cancer.
Nicholson J.M. and
Cimini D. (2011)
Adv. Canc. Res., 112: 43-75.
29
Changes in gene expression and
cellular architecture in an ovarian cancer progression model.
Creekmore A.L., Silkworth W.T.,
Cimini D., Jensen R.V., Roberts P.C., and
Schmelz E.M. (2011)
PLoS ONE, 6(3): e17676.
28
Merotelic kinetochore
attachment: causes and effects.
Gregan J., Polakova S., Zhang L., M. Tolic-Nørrelykke I., and
Cimini
D. (2011).
Trends Cell Biol., 21: 374-381.
============
2009
============
27
Computer
simulations predict that chromosome movements and rotations accelerate mitotic
spindle assembly
without compromising accuracy.
Paul R., Wollman R., Silkworth W.T., Nardi I.K.,
Cimini D., and Mogilner A.
(2009).
Proc. Natl. Acad. Sci. U.S.A., 106: 15708-15713.
26
Multipolar
spindle pole coalescence is a major source of kinetochore mis-attachment and
chromosome
mis-segregation in cancer cells.
Silkworth W.T., Nardi I., Scholl L.M., and
Cimini D. (2009).
PloS ONE, 4(8): e6564.
25
Telomere and Chromosome
Segregation.
Sgura A. and
Cimini D. (2009).
In “Telomeres: Function, Shortening and Lengthening”. Leonardo Mancini,
ed. Nova Science Publishers.
============
2008
============
24
Merotelic
kinetochore orientation, aneuploidy, and cancer.
Cimini D. (2008).
Biochim. Biophys. Acta, 1786: 32-40.
============
2007
============
23
Detection
and correction of merotelic kinetochore orientation by Aurora B and its
partners.
Cimini D. (2007).
Cell Cycle, 6: 1558-1564.
============
2006
============
22
Kinetochore
microtubule dynamics and attachment stability are regulated by Hec1.
DeLuca J.G., Gall W.E., Ciferri C.,
Cimini D., Musacchio A., and Salmon
E.D. (2006).
Cell, 127: 969-982.
[
Cited
in Faculty of 1000]
21
Aurora
kinase promotes turnover of kinetochore microtubules to reduce chromosome
segregation errors
due to merotelic kinetochore
orientation.
Cimini D., Wan X., Hirel C.B., and Salmon E.D. (2006).
Curr. Biol., 16: 1711-1718.
[Highlighted in a Dispatch by Zhang and Walczak in Curr. Biol., 16: r677-r678]
20
Kinesin
5-independent poleward flux of kinetochore microtubules in PtK1 cells.
Cameron L.A., Yang G.,
Cimini D., Canman J.C., Kisurina-Evgenieva O.,
Khodjakov A., Danuser G.,
and Salmon E.D.
(2006).
J. Cell Biol., 173: 173-179, [Cover article]
[
Cited
in Faculty of 1000]
19
Chromosomes
can congress to the metaphase plate before biorientation.
Kapoor T.M., Lampson M.A., Hergert P., Cameron L.,
Cimini D., Salmon E.D.,
McEwen B.F., and Khodjakov A. (2006).
Science, 311: 388-391.
[Cover article; Comment by Rebecca Heald in Science, 311:388-391]
[
Cited
in Faculty of 1000]
============
2005
============
18
Aneuploidy:
a matter of bad connections.
Cimini D., Degrassi F. (2005).
Trends Cell Biol., 15: 442-451.
17
Merotelic
kinetochores in mammalian tissue cells.
Salmon E.D.,
Cimini D., Cameron L.A., and DeLuca J.G. (2005).
Philos. Trans. R. Soc. Lond. B Biol. Sci., 360: 553-568.
16
The
Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly
checkpoint.
De Antoni A., Pearson C.G.,
Cimini D., Canman J.C., Sala V., Nezi L.,
Mapelli M., Sironi L., Faretta M., Salmon E.D.,
and
Musacchio A. (2005).
Curr. Biol., 15: 214-225.
[
Cited in Faculty of
1000].
============
2004
============
15
Anaphase
spindle mechanics prevent mis-segregation of merotelically oriented
chromosomes.
Cimini D., Cameron L.A., and Salmon E.D. (2004).
Curr. Biol., 14: 2149-2155.
[Dispatch by Tarun M. Kapoor in Curr. Biol., 14: R1011-R1013; Research Roundup article by
William A. Wells
in J. Cell Biol., 168: 10;
Cited in Faculty of
1000]
============
2003
============
14
Merotelic
kinetochore orientation occurs frequently during early mitosis in mammalian
tissue cells, and error
correction is achieved by two different
mechanisms.
Cimini D., Moree B., Canman J.C., and Salmon E.D. (2003).
J. Cell Sci., 116: 4213-4225.
[
Cited in Faculty of
1000]
13
Histone
hyperacetylation in mitosis prevents sister chromatid separation and produces
chromosome
segregation defects.
Cimini D., Mattiuzzo M., Torosantucci L., and Degrassi F. (2003).
Mol. Biol. Cell., 14: 3821-3833.
============
2002
============
12
Merotelic
kinetochore orientation versus chromosome mono-orientation in the
origin of lagging chromosomes
in human
primary cells.
Cimini D., Fioravanti D., Salmon E.D., Degrassi F. (2002).
J. Cell Sci., 115 (3): 507-515.
============
2001
============
11
Merotelic
kinetochore orientation is a major mechanism of aneuploidy in mitotic
mammalian tissue cells.
Cimini D., Howell B.J., Maddox P., Khodjakov A., Degrassi F., and Salmon
E.D. (2001).
Journal of Cell Biology, 153: 517-527.
============
1999
============
10
Differences
in malsegregation rates
obtained by scoring ana-telophases or binucleate cells.
Cimini D., Tanzarella C., and Degrassi F. (1999).
Mutagenesis, 14: 563-568.
09
A
fraction of mouse sperm chromatin is organized in
nucleosomal hypersensitive domains
enriched in retroposon DNA.
Pittoggi C., Renzi L., Zaccagnini G.,
Cimini D., Degrassi F., Giordano R.,
Magnano A.R., Lorenzini R., Lavia P.,
and Spadafora
C. (1999).
Journal of Cell Science, 112: 3537-3548.
08
Analysis
of chromosome loss and non-disjunction in
cytokinesis-blocked lymphocytes of 24 male subjects.
Carere A., Antoccia A.,
Cimini D., Crebelli R., Degrassi F., Leopardi P.,
Marcon F., Sgura A., Tanzarella C.,
and Zijno A.
(1999).
Mutagenesis, 14: 491-496.
07
Development
of animal models for
adeno-associated virus site-specific integration.
Rizzuto G., Gorgoni B., Cappelletti M., Lazzaro D., Gloaguen I., Poli V., Sgura A.,
Cimini D., Ciliberto G., Cortese R.,
Fattori E., and La Monica N. (1999).
J. Virology, 73: 2517-2526.
============
1998
============
06
Simultaneous
inhibition of contractile ring and central spindle formation in mammalian cells
treated
with cytochalasin B.
Cimini D., Fioravanti D., Tanzarella C., and Degrassi F. (1998).
Chromosoma, 107: 479-485.
[Erratum]
05
Targeted integration of adeno-associated virus-derived
plasmids in transfected human cells.
Pieroni L., Fipaldini C., Monciotti A.,
Cimini D., Sgura A., Fattori E.,
Epifano O., Cortese R., Palombo F.,
and La Monica
N. (1998).
Virology, 249: 249-259.
04
Genetic
effects of petroleum fuels. II. Analysis of chromosome
loss and hyperploidy in peripheral lymphocytes
of gasoline station attendants by
fluorescence in situ hybridization
techniques.
Carere A., Antoccia A.,
Cimini D., Crebelli R., Degrassi F., Leopardi P.,
Marcon F., Sgura A., Tanzarella C.,
and Zijno A.
(1998).
Environ. Mol. Mutagenesis, 32: 130-138.
============
1997
============
03
Topoisomerase
II inhibition in mitosis produces numerical and structural chromosomal
aberrations
in human fibroblasts.
Cimini D., Antoccia A., Tanzarella C., and Degrassi F. (1997).
Cytogenet. Cell Genet., 76: 61-67.
============
1996
============
02
The
detection and evaluation of aneugenic chemicals.
Parry J.M., .......,
Cimini D., ......., Hess P. (1996).
Mutat. Res., 353: 11-46.
01
Effects
of 5-azacytidine on the centromeric region of human fibroblasts studied by CREST
staining and in situ
hybridization on cytokinesis-blocked
cells.
Cimini D., Tanzarella C., and Degrassi F. (1996).
Cytogenet. Cell Genet., 72: 219-224.